Renal decompensation:
Normal glomerular filtration rate of 120 ml per minute. This period, glomerular filtration rate decreased to 30-60 ml / min, reduced by about 20% -25% of renal units. Although the loss of the renal reserve capacity, but excretion metabolites, regulate water, electrolyte and acid-base balance capacity is still good, so clinical, serum muscle enzymes and blood urea nitrogen is usually normal or sometimes slightly elevated.
Renal failure, how the stage? Azotemia (decompensated):
Glomerular filtration rate decreased to 25 ml / min, a decrease of 50% -70% of renal units, the concentration of renal dysfunction, nocturia or polyuria, varying degrees of anemia, often azotemia, creatinine urea nitrogen levels. Clinical weakness, loss of appetite, nausea, and mild systemic discomfort. Such as ignoring the protection of renal function or body of the extra load, such as severe vomiting, diarrhea, caused by hypovolemia, severe infection and the use of nephrotoxic drugs, can cause renal function rapidly diminished while the failure.
How staging renal failure?
Renal failure (uremia early):
Glomerular filtration rate decreased to 10-15 ml per minute, reduced by about 70% -90% of renal units, renal function is severely impaired, unable to maintain the body's metabolism and electrolyte and acid-base balance. Impossible to maintain the body's inner stability, resulting in serum creatinine, blood urea nitrogen were significantly increased urine concentration dilution dysfunction, acidosis, sodium retention, low calcium, high phosphorus, potassium and other imbalance performance. May have obvious anemia and gastrointestinal symptoms such as nausea, vomiting, loss of appetite. May also have neuropsychiatric symptoms such as fatigue, inattention, lack of energy.
How staging renal failure?
Uremia(end stage renal failure):
Glomerular filtration rate decreased to less than 10 ml per minute, -15 ml, more than 90% reduction in nephron, this period is the late chronic renal failure, the above-mentioned clinical symptoms of renal failure more obvious, the function of multiple organ failure.serious imbalances such as the gastrointestinal tract, nervous system, cardiovascular, hematopoietic system, respiratory system, skin and metabolic systems.
Clinically manifested as nausea, vomiting, irritability, increased blood pressure, palpitation, chest tightness, not supine, breathing difficulties, severe anemia, convulsions, coma and severe cases often hyperkalemia, hyponatremia, low calcium, high phosphorus blood syndrome. This need to rely on dialysis to sustain life. Often may be due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.
Normal glomerular filtration rate of 120 ml per minute. This period, glomerular filtration rate decreased to 30-60 ml / min, reduced by about 20% -25% of renal units. Although the loss of the renal reserve capacity, but excretion metabolites, regulate water, electrolyte and acid-base balance capacity is still good, so clinical, serum muscle enzymes and blood urea nitrogen is usually normal or sometimes slightly elevated.
Renal failure, how the stage? Azotemia (decompensated):
Glomerular filtration rate decreased to 25 ml / min, a decrease of 50% -70% of renal units, the concentration of renal dysfunction, nocturia or polyuria, varying degrees of anemia, often azotemia, creatinine urea nitrogen levels. Clinical weakness, loss of appetite, nausea, and mild systemic discomfort. Such as ignoring the protection of renal function or body of the extra load, such as severe vomiting, diarrhea, caused by hypovolemia, severe infection and the use of nephrotoxic drugs, can cause renal function rapidly diminished while the failure.
How staging renal failure?
Renal failure (uremia early):
Glomerular filtration rate decreased to 10-15 ml per minute, reduced by about 70% -90% of renal units, renal function is severely impaired, unable to maintain the body's metabolism and electrolyte and acid-base balance. Impossible to maintain the body's inner stability, resulting in serum creatinine, blood urea nitrogen were significantly increased urine concentration dilution dysfunction, acidosis, sodium retention, low calcium, high phosphorus, potassium and other imbalance performance. May have obvious anemia and gastrointestinal symptoms such as nausea, vomiting, loss of appetite. May also have neuropsychiatric symptoms such as fatigue, inattention, lack of energy.
How staging renal failure?
Uremia(end stage renal failure):
Glomerular filtration rate decreased to less than 10 ml per minute, -15 ml, more than 90% reduction in nephron, this period is the late chronic renal failure, the above-mentioned clinical symptoms of renal failure more obvious, the function of multiple organ failure.serious imbalances such as the gastrointestinal tract, nervous system, cardiovascular, hematopoietic system, respiratory system, skin and metabolic systems.
Clinically manifested as nausea, vomiting, irritability, increased blood pressure, palpitation, chest tightness, not supine, breathing difficulties, severe anemia, convulsions, coma and severe cases often hyperkalemia, hyponatremia, low calcium, high phosphorus blood syndrome. This need to rely on dialysis to sustain life. Often may be due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.
