The treatment of lupus nephritis are the following, as you choose. [Click to
consult the experts
Asymptomatic proteinuria treatment: (urine protein> 2g/24h) available glucocorticoids, as appropriate, increase Tripterygium preparations and prednisone combination with cytotoxic drugs, have a certain effect; asymptomatic hematuria, can be used Tripterygium preparations (conventional-dose or double dose) or CTX treatment. Conditional best choice of drugs under the renal pathological types.
(2) the treatment of heavy systemic lupus erythematosus: associated with acute nephritic syndrome or rapidly progressive nephritic syndrome, renal biopsy showed diffuse proliferative glomerulonephritis, or crescentic nephritis, renal insufficiency, standard hormone therapy and CTX pulse therapy should be given; or methylprednisolone pulse therapy, daily 1.0g, static points 3 to 5 days for a course, following a moderate dose of prednisone to maintain, if necessary, 7 to 10 days, can be repeated once, and generally not more than three courses. When the above method is ineffective or serious condition, plasma exchange therapy may be considered; cyclosporin trial can not be used by CTX neomycin A, mycophenolate mofetil. With acute severe renal insufficiency, severe high blood volume, heart failure when emergency dialysis, and out of danger, to create the conditions for drug treatment and gain time.
Constant of proteinuria in patients with treatment performance of systemic lupus erythematosus: without the constant of proteinuria, or azotemia and renal pathology of chronic diseases to become the master, usually not long-term use of prednisone therapy and cytotoxic drugs.
(4) treatment by Chinese medicine: Chinese medicine syndrome differentiation may improve efficacy, reduce symptoms and reduce the side effects of western medicine.
General treatment: including rest, diet, diuretic, lowering blood pressure, anticoagulation and prevention of various complications, refer to the treatment of primary glomerular disease should be based on the patient's condition.
(6) was the treatment of nephrotic syndrome: the urine red blood cells small, stable renal function or renal biopsy showed membranous lupus nephritis, should be preferred to prednisone 0.8 ~ 1.0mg/kg.d 2 to 4 ineffective weeks after the addition of CTX, if accompanied by renal dysfunction, severe hypertension, renal biopsy showed marked hyperplasia of the glomerular or the occurrence of the pathological type of change should be given the standard hormone therapy plus CT lupus nephritis X pulse therapy.
End-stage treatment: chronic renal failure. Also need to be reminded that patients with lupus nephritis, general clinical drugs for the treatment of lupus nephritis have renal toxicity, so patients should be aware that in the treatment process, often the efficacy and risks coexist. But doctors at the time of treatment will be fully the trade-offs, according to the condition of the patient and drug characteristics, use, where appropriate, while the rich use of drugs to a minimum, so patients should be assured the right medication under the guidance of a doctor!
Asymptomatic proteinuria treatment: (urine protein> 2g/24h) available glucocorticoids, as appropriate, increase Tripterygium preparations and prednisone combination with cytotoxic drugs, have a certain effect; asymptomatic hematuria, can be used Tripterygium preparations (conventional-dose or double dose) or CTX treatment. Conditional best choice of drugs under the renal pathological types.
(2) the treatment of heavy systemic lupus erythematosus: associated with acute nephritic syndrome or rapidly progressive nephritic syndrome, renal biopsy showed diffuse proliferative glomerulonephritis, or crescentic nephritis, renal insufficiency, standard hormone therapy and CTX pulse therapy should be given; or methylprednisolone pulse therapy, daily 1.0g, static points 3 to 5 days for a course, following a moderate dose of prednisone to maintain, if necessary, 7 to 10 days, can be repeated once, and generally not more than three courses. When the above method is ineffective or serious condition, plasma exchange therapy may be considered; cyclosporin trial can not be used by CTX neomycin A, mycophenolate mofetil. With acute severe renal insufficiency, severe high blood volume, heart failure when emergency dialysis, and out of danger, to create the conditions for drug treatment and gain time.
Constant of proteinuria in patients with treatment performance of systemic lupus erythematosus: without the constant of proteinuria, or azotemia and renal pathology of chronic diseases to become the master, usually not long-term use of prednisone therapy and cytotoxic drugs.
(4) treatment by Chinese medicine: Chinese medicine syndrome differentiation may improve efficacy, reduce symptoms and reduce the side effects of western medicine.
General treatment: including rest, diet, diuretic, lowering blood pressure, anticoagulation and prevention of various complications, refer to the treatment of primary glomerular disease should be based on the patient's condition.
(6) was the treatment of nephrotic syndrome: the urine red blood cells small, stable renal function or renal biopsy showed membranous lupus nephritis, should be preferred to prednisone 0.8 ~ 1.0mg/kg.d 2 to 4 ineffective weeks after the addition of CTX, if accompanied by renal dysfunction, severe hypertension, renal biopsy showed marked hyperplasia of the glomerular or the occurrence of the pathological type of change should be given the standard hormone therapy plus CT lupus nephritis X pulse therapy.
End-stage treatment: chronic renal failure. Also need to be reminded that patients with lupus nephritis, general clinical drugs for the treatment of lupus nephritis have renal toxicity, so patients should be aware that in the treatment process, often the efficacy and risks coexist. But doctors at the time of treatment will be fully the trade-offs, according to the condition of the patient and drug characteristics, use, where appropriate, while the rich use of drugs to a minimum, so patients should be assured the right medication under the guidance of a doctor!
