Hemodialysis causes anemia do?

Hemodialysis patients accumulated a large amount of blood loss, mainly dialyzer clotting, rupture, back when the blood dialyzer and pipeline flushing is not complete, blood residues more relevant. On the other hand, blood tests are also the main reason for loss of blood. Female dialysis patients ovulation disorders, menstruation and menstrual bleeding between periods, after increasing and often caused by heparin occult gastrointestinal bleeding. Does not mean hemodialysis aggravate renal anemia Instead adequate dialysis clearable Toxic increase patient appetite improve systemic nutritional status eliminate affect erythrocyte lifetime uremia environment reduce erythrocytes autolysis increase marrow red Department for erythropoietin response, improved coagulation and platelet function, inhibition of the skin, gastrointestinal tract and other parts of the bleeding. Therefore, if adequate dialysis, hemodialysis patients anemia can be improved.
Affect the efficacy of erythropoietin main factors:
1, the infection can be significantly reduced on erythropoietin response to control infection and inflammation after the resumption. Its possible through inflammatory cytokines mediated inhibition with erythropoietin;
2, chronic blood loss can lead to iron deficiency and erythropoietin response to weaken;
3, aluminum intoxication affect the performance of the bone marrow to extend the time required to achieve the target hemoglobin;
4, folic acid and vitamin B12 is necessary for hemoglobin synthesis substances, if deficiency can lead to lack of raw materials, affecting the efficacy of erythropoietin;
5, malnutrition can lead to lack of raw materials synthesis of hemoglobin, and so on.